This is not what people mean when they say, “Write what you know.” If you’re ever tempted to write a screenplay about a screenwriter’s heroic efforts to make it big in Hollywood, just step away from the keyboard and go outside for a nice long walk. There are only a handful of scripts on this topic that are any good (including one of my favorite movies of all time, “Adaptation” by Charlie Kaufman) and those were only successful in spite of the subject matter.
If you look at Kaufman’s script, it’s clear that he was trying to figure out a way to break every single rule in screenwriting and still end up with a good story, which he does. (BTW, am I the only person who thinks the "Happy Together" death scene is hilarious? It cracks me up every time!) Charlie Kaufman is ten times smarter than all of the screenwriters on this planet combined, so he is the only person who can actually pull this off. We mortals must choose subjects that everyone can relate to, which doesn’t include the problems of struggling screenwriters.